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Cranio-osteoarthropathy

ORPHA:1525· ICD-10 M89.4

Definition

Cranio-osteoarthropathy (COA) is a form of primary hypertrophic osteoarthropathy characterized by delayed closure of the cranial sutures and fontanels, digital clubbing, arthropathy, and periostosis.

Prevalence
<1 / 1 000 000
Inheritance
Autosomal recessive
Age of onset
Childhood