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Progressive non-fluent aphasia

ORPHA:100070· ICD-10 G31.0

Definition

Progressive non-fluent aphasia (PNFA) is a form of frontotemporal dementia (FTD), characterized by agrammatism, laborious speech, alexia, and agraphia, frequently accompanied by apraxia of speech (AOS). Language comprehension is relatively preserved.

Prevalence
1-9 / 100 000
Inheritance
Multigenic/multifactorial, Not applicable
Age of onset
Adult