vitalwiki

TRICON

RxNorm 999799· ORAL

Vitamin C [EPC], Vitamin B12 [EPC] · Nnodum Pharmaceuticals

Indications and usage

INDICATIONS AND USAGE TRICON™ is a multifactor preparation effective in the treatment of anemias that respond to oral hematinics, including pernicious anemia and other megaloblastic anemias and also irondeficiency anemia. Therapeutic quantities of hematopoietic factors that are known to be important are present in the recommended daily dose.

Dosage and administration

DOSAGE AND ADMINISTRATION One capsule twice a day. (Two capsules daily produce a standard response in the average uncomplicated case of pernicious anemia.)

Contraindications

CONTRAINDICATIONS Hemochromatosis and hemosiderosis are contraindications to iron therapy.

Pregnancy

Pregnancy Teratogenic Effects Pregnancy Category C: Animal reproduction studies have not been conducted with TRICON™ Capsules. It is also not known whether TRICON™ Capsules can cause fetal harm when administered to pregnant women or can affect reproduction capacity. TRICON™ Capsules should be given to pregnant women only if clearly needed.

Nursing mothers

Nursing Mothers It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when TRICON™ is administered to a nursing woman.

Adverse events

Most frequently reported events (FDA FAERS). Report frequency does not imply causation.

  • death2
  • headache2
  • abdominal pain1
  • activities of daily living impaired1
  • acute kidney injury1
  • cataract1
  • chronic kidney disease1
  • drug ineffective1
  • dysaesthesia1
  • eye irritation1
  • eye pain1
  • eyelid irritation1
  • fatigue1
  • foreign body sensation in eyes1
  • gait disturbance1
  • heart rate irregular1

Adverse reactions (label)

ADVERSE REACTIONS Rarely, iron in therapeutic doses produces gastrointestinal reactions, such as diarrhea or constipation. Reducing the dose and administering it with meals will minimize these effects in the iron-sensitive patient. In extremely rare instances, skin rash suggesting allergy has been noted following the oral administration of liver-stomach material. Allergic sensitization has been reported following both oral and parenteral administration of folic acid.

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